GlaxoSmithKline plc

 Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons

In accordance with DTR 3.1.4 R(1)(a) I give details of changes in the interests of Mr W Louv, a Person Discharging Managerial Responsibilities, in the American Depositary Shares ('ADSs') of GlaxoSmithKline plc (the 'Company'). The Company was advised on 11 December 2014 that Mr W Louv sold 14,999.034 ADSs on 8 December 2014 at a price of $45.86 per ADS.

V A Whyte

Company Secretary

11 December 2014