GlaxoSmithKline plc

Notification of Transactions of Directors, Persons Discharging

Managerial Responsibility or Connected Persons

In accordance with DTR 3.1.4R(1)(a) GlaxoSmithKline plc ('GSK') was advised on 16 January 2015, of changes in the interests of the following Persons Discharging Managerial Responsibilities, following increases in their actual interests in American Depositary Shares (ADSs), at a price of $41.78 per ADS, following the re-investment of dividends paid on ADSs held in the vested portion of the GSK 2009 Deferred Annual Bonus Plan Post-Tax awards.

V A Whyte

Company Secretary

20 January 2015