GlaxoSmithKline plc

 Notification of Transactions of Directors, Persons Discharging Managerial Responsibilities or Connected Persons

In accordance with DTR 3.1.4 R(1)(c) I give details of changes in the interests of Dr P J T Vallance, a Person Discharging Managerial Responsibilities, in the Ordinary Shares of GlaxoSmithKline plc ('GSK'). GSK was advised on 27 July 2015 that Dr P J T Vallance's Connected Person, Dr S Dexter, acquired 291 GSK Ordinary Shares, at a price of 1372.05 pence per Share, following the re-investment of the dividend paid to shareholders on 9 July 2015.

V A Whyte

Company Secretary

27 July 2015