The head of the regional US Federal Reserve Bank of Boston called for a faster pace of rate hikes than his colleagues in 2017.
Sterling saw a rather "tame" reaction to Brexit negotiations being activated by Prime Minister Theresa May, rising from a midday funk to recoup most of its earlier softness against the US dollar.
These were the movements in some of the most widely-followed 10-year sovereign bond yields:.
Weekly US oil inventories rose slightly during the latest reference week, albeit alongside sharp drops in product stockpiles.
Equities in London fended off Brexit jitters to close higher, having overcome some softness seen around the time Prime Minister Theresa May fired the starting gun on UK divorce talks with the EU.
Crude-oil futures made modest gains on Wednesday as the black liquid benefited from supply distributions in Libya, a drop in March production from United Arab Emirates (UAE) and speculation of cartel Opec extending its 2016 output pledges.
The US central bank is watching the White House's new policies with keen interest, but thus far their potential impact on the economy had only been factored into their forecasts somewhat, its second-highest ranking official said.
A top US rate-setter reiterated his relatively dovish stance on monetary policy on Wednesday, telling his audience he still worried that interest rates might be headed back towards the 'zero-bound' at some point in the future.
Sterling had a torrid time on key crosses Tuesday as a pall of pre-Brexit nerves again weighed on sentiment, although the British unit's downcast performance was well and truly outpaced by hefty falls in South Africa's already besieged rand.
Crude-oil futures are bouncing back on Tuesday afternoon after emerging from their lows of last week, but the overall mood towards the black liquid is considered to remain bearish.
America cut its trade shortfall with the rest of the world in February, amid a sharp drop in the pace of purchases of automobiles and consumer products from overseas.