Change to Director's Details - Dr Moncef Slaoui

GlaxoSmithKline plc (the "Company") today confirms that Dr Moncef Slaoui, an Executive Director, is appointed Chairman, Vaccines, with immediate effect.

This appointment will ensure more focused management of the Company's Vaccines business in advance of the completion of the proposed 3 part transaction with Novartis announced earlier this year. Dr Slaoui will continue to provide scientific and technical counsel on pharmaceutical R&D activities to the CEO and Board.

Dr Slaoui was previously Chairman, Global R&D and Vaccines.

V A Whyte

Company Secretary

22 October 2014