GW Pharmaceuticals tests epilepsy drug in man as FDA softens stance

A.B. | ShareCast | 18 Sep, 2013 11:09 - Updated: 11:59 | | |

Drugs

Cannabis-derived drug developer GW Pharmaceuticals has begun human trials of its epilepsy treatment.

The AIM- and Nasdaq-listed company said the novel drug candidate, currently named GWP42006, was one of its most promising and looked to have significantly fewer side effects than currently approved anti-epileptic drugs.

Dr. Stephen Wright, Director of Research and Development at the company said advancing GWP42006 to a first dose in man was a significant milestone in the development of this candidate.

“The decision to progress into Phase 1 follows several years of highly promising pre-clinical research," he added.

"We believe that GWP42006 has the potential to become an important advance in the treatment of epilepsy, a condition for which there remains a substantial unmet medical need."

Research with the Reading School of Pharmacy in Buckinghamshire has shown that GWP42006 not only exerts significant ability to treat seizures in a wide range of preclinical models of seizure and epilepsy, but is also better tolerated by patients compared to existing anti-epileptic drugs.

The company has been encouraged by recent interest in its products in the US. That arose after the pharmaceutical regulator, the Food and Drug Administration [FDA], allowed US epilepsy specialists and patient organizations to carry out treatment on a small number of pediatric epilepsy patients with a cannabidiol [CBD] formulation supplied by GW. These activities may generate initial evidence to add CBD as a further pipeline candidate for clinical evaluation in epilepsy.

Recent third quarter showed net cash of $66.3m thanks to a US IPO in May that raised $30.4m.

Shares in GWP were up 1.4% to 72p at 11:12 on Wednesday.

OH

More news

17:59 Experts say oil prices must drop much further to hit shale oil industry

A modest decline in oil prices from current levels could seriously impact the finances of some of the smaller American shale oil producers, but a drop of at least another $20 per barrel would be needed to choke off the US oil boom, some experts believe.

17:23 Four dead as plane crashes into airport building in Kansas

Four people died and five were left injured as a small plane on Thursday crashed into an airport building in Wichita, Kansas.

17:20 Europe close: Stocks pick up after Eurozone, US data

European stocks rebounded as investors digested a batch of data in the Eurozone and the US.

17:25 London close: FTSE ends session with modest gains

The top tier closed slightly higher on Thursday, as a strong performance by Smith & Nephew was offset by losses amongst the mining sector.

17:11 Market overview: Miners follow gold lower, StanChart drops

1630:Close As is often the case, the last hour of trading in New York tends to provide reliable signals as to the direction of trading on the next day. That was the case on Wednesday; in the last 60 minutes of the session US stocks began to climb back from their intraday lows, following the Fed’s policy decision, to close nearly unchanged. That recovery continued on Thursday and fed through into UK equities. Smith&Nephew was at the top of the leader-board following its latest quarterly results. Miners were weakest, weighed down by strength in the US dollar and prospects for the first rate increase in the Fed funds rate in over eight years to arrive at some point in 2015. StanChart was a standout faller on the back of reports that US authorities have re-opened an investigation into allegations the lender broke the international sanctions regime against Iran. FTSE 100 up 10 points to 6,464.

16:59 Wandisco CFO sells shares post-exercise

In a quiet day for deals, chief financial officer of Wandisco, Paul Harrison, has sold 68,463 of the 138,784 shares which he received following their exercise.

16:49 NHS workers to go on strike next month, reports say

Nurses and midwives from the NHS are expected to go on strike next month, reports have said.

16:45 Ebola alert at Dublin airport, police describe as minor security incident

Irish authorities on Thursday activated their protocol against Ebola at Dublin airport after a passenger claimed he was infected with the tropical virus.

16:37 Friday preview: Investors look ahead to RBS, WPP, Eurozone inflation, US data

Royal Bank of Scotland (RBS) results, Eurozone inflation and US data on both personal spending and consumer confidence will be high on Friday’s agenda.

16:36 Mondi receives upgraded credit rating

International packaging and paper group Mondi has announced that the recent upgrade of the company's credit rating.

Advertising

HIGHLIGHTS

vuelo ebola
Ebola latest: North Korea to quarantine all foreigners

Rolling Ebola coverage. Refresh for updates.

VIDEOS

Support and resistance levels Support and resistance levels 30th october 2014
REGISTER NOW!