Meldex International plc (the 'Company')

Changes to the Board of Directors

London, UK, 4 September 2008: Meldex (AIM: MDX), the specialty pharma and healthcare company announces that Richard Trevillion, CEO, is to leave the Company, and ceases to have any executive responsibilities with immediate effect.

The Board is actively looking for a replacement and as an interim measure Dr Jim Murray will become Executive Chairman with immediate effect. The remainder of the Executive Board is comprised of Helmut Kerschbaumer, CFO, Klaus Kuehne as COO and Steve Martin as CDO.

The Board is confident that the Executive Board is well equipped to manage and run Meldex in an effective and thorough manner.

The Company will announce its Interim Results as planned by the end of September. 

For further information:

Buchanan Communications                     + 44 (0) 20 7466 5000

Rebecca Skye Dietrich

FinnCap, NOMAD                                      + 44 (0) 20 7600 1658

Clive Carver

About Meldex International Plc

Meldex International plc is an innovative specialty pharmaceutical and OTC product Company. Listed on London's AIM in May 2003, the Company has over 80 patents granted or in application within 24 patent families and has product development agreements and strategic alliances with several global healthcare companies. Meldex has acquired sales and marketing resources within Europe and the US as a launch mechanism for its own pharmaceutical products. Meldex acquired the Melbrosin business in June 2007. Melbrosin's focus is on consumer over the counter health care products based on substances of natural and plant origin which are developed into consumer orientated brands then scaled, produced and distributed by Melbrosin. The Melbrosin complements the prescription pharmaceutical sales and marketing business created and expanded in 2006.

The business continues to develop innovative delivery mechanisms enhancing both its own product range and those of selected partners using its proprietary XGELTM polymer technology. For further information please go to www.meldexinternational.com

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