Name of exempt principal trader

Credit Suisse Securities (Europe) Limited

Company dealt in

Protherics Plc

Class of relevant security to which the dealings being disclosed relate (Note 1)

Ordinary Shares

Date of dealing

06-Oct-2008

Total number of securities purchased

Highest price paid (Note 3)

Lowest price paid (Note 3)

422962

0.41 (GBP)

0.3899 (GBP)

Total number of securities sold

Highest price received (Note 3)

Lowest price received (Note 3)

422962

0.4051 (GBP)

0.39 (GBP)

Product name, e.g. CFD

Long/short (Note 4)

Number of securities (Note 5)

Price per unit (Note 3)

Product name,e.g. call option

Writing, selling, purchasing, varying etc.

Number of securities to which the option relates (Note 5)

Exercise price

Type, e.g. American, European etc.

Expiry date

Option money paid/received per unit (Note 3)

Product name, e.g. call option

Number of securities

Exercise price per unit (Note 3)

Full details of any agreement, arrangement or understanding between the person disclosing and any other person relating to the voting rights of any relevant securities under any option referred to on this form or relating to the voting rights or future acquisition or disposal of any relevant securities to which any derivative referred to on this form is referenced. If none, this should be stated.

Date of disclosure

07-Oct-2008 09:23:02

Contact name

Collins,Carolyn/ Crawley, Simon

Telephone number

44 20 7888 0241

Name of offeree/offeror with which connected

BTG PLC

Nature of connection (Note 6)

ADVISOR