Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons

I give below details of changes in interests in the Ordinary shares of GlaxoSmithKline plc in respect of the under-mentioned person:

Mr S M Bicknell acquired a beneficial interest in 9 Ordinary shares arising from the re-investment of dividends under a Personal Equity Plan on 6 October 2008 at £12.13 per share.

The Company and the above named individual were advised of this transaction on

7 October 2008.

This notification relates to a transaction notified in accordance with Disclosure and Transparency Rule 3.1.4R(1)(a).

V A Whyte

Deputy Company Secretary

7 October 2008

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