21 October 2016

Avacta Group plc

("Avacta", "the Group" or "the Company")

Director's Dealing

Avacta Group plc (AIM: AVCT), the developer of Affimer® biotherapeutics, research and diagnostic reagents, announces that Dr. Mike Owen, a Non-Executive Director of the Group, has purchased today 7,763 Ordinary Shares of 10p each in the Group at a price of 90.0 pence per share.

Following this transaction, Dr Owen's total interest in the Group is 7,763 Ordinary Shares of 10p each, representing less than 0.1% of Avacta's issued share capital.

The information communicated in this announcement is inside information for the purposes of Article 7 of Regulation 596/2014.

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Notes to Editors

Avacta Group plc (www.avacta.com)

Avacta's principal focus is on its proprietary Affimer^® technology which is a novel engineered alternative to antibodies that has wide application in Life Sciences for diagnostics, therapeutics and general research and development.

Antibodies dominate markets worth in excess of $75bn despite their shortcomings. Affimer technology has been designed to address many of these negative performance issues, principally; the time taken to generate new antibodies, the reliance on an animal's immune response, poor specificity in many cases, and batch to batch variability. Affimer technology is based on a small protein that can be quickly generated to bind with high specificity and affinity to a wide range of targets to enable diagnostics, research assays and therapeutics.

Avacta has a pre-clinical therapeutic development programme with an in-house focus on immuno-oncology and bleeding disorders as well as partnered development programmes. Avacta is commercialising non-therapeutic Affimer reagents through licensing to developers of life sciences research tools and diagnostics.

Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them